Crystal Structure of Bacillus subtilis -Amylase in Complex with Acarbose
نویسندگان
چکیده
The crystal structure of Bacillus subtilis -amylase, in complex with the pseudotetrasaccharide inhibitor acarbose, revealed an hexasaccharide in the active site as a result of transglycosylation. After comparison with the known structure of the catalytic-site mutant complexed with the native substrate maltopentaose, it is suggested that the present structure represents a mimic intermediate in the initial stage of the catalytic process.
منابع مشابه
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